Description

Methandrostenolone (Danabol DS) 10 mg

Brand: DS
Category: Oral AAS Research Compound
Content: 500 tablets | 10 mg per tablet (5,000 mg total)
Price: €69
Manufactured in: Thailand

🧪 Product Overview

Methandrostenolone 10 mg, commonly known as Danabol DS or “D-Bol,” is one of the earliest and most
extensively studied synthetic anabolic-androgenic steroids (AAS). As a structurally modified testosterone derivative,
it serves as a robust model compound for exploring anabolic pathways, nitrogen retention, metabolic regulation,
and hepatic processing of 17-α-alkylated oral steroids.

Originally introduced in the 1950s by CIBA under the brand Dianabol, methandrostenolone has a long research history
with well-established pharmacodynamic and toxicological profiles. The Danabol DS formulation offers reliable
oral bioavailability suitable for controlled-dose in-vitro and pre-clinical models.

✅ Key Research Highlights

Protein synthesis & nitrogen retention:
Stimulates AR-mediated transcription and anabolic gene expression, enhancing muscle-cell protein synthesis.

Muscle hypertrophy modeling:
Used in research to evaluate fat-free mass gain, potassium balance, and anabolic-to-catabolic shifts.

Hepatic metabolism studies:
As a 17-α-alkylated steroid, it is integral to research on liver enzyme induction, cholestasis, and hepatocellular stress.

Comparative AAS research:
Reference standard in studies comparing potency, toxicity, and metabolic profiles of oral anabolic steroids.

🧬 Suggested Laboratory Applications

• Androgen receptor–mediated transcription and anabolic signaling
• Protein synthesis & nitrogen balance modeling
• Muscle hypertrophy and metabolic performance studies
• Liver-toxicity screening for 17-α-alkylated compounds
• Endocrine disruption research (HPG-axis suppression models)

📊 Technical Specifications

❄️ PubChem-Supported Research Insights

• Binds AR with strong anabolic transcriptional output
• Promotes nitrogen retention and protein synthesis in metabolic studies
• 17-α-alkylated design increases both oral stability and hepatic strain
• Used broadly in pharmacology as a reference standard for anabolic potency
• Linked to lipid imbalance and hormonal feedback suppression in chronic models

⚠️ Documented Research Side Effects

• Cholestatic liver injury, peliosis, adenomas/tumors (dose & duration dependent)
• Cardiovascular stress: ↓ HDL, ↑ LDL, potential hypertrophic markers
• Endocrine/HPTA suppression and hormonal imbalance
• Oxidative stress and altered gene expression in chronic models

🧯 Handling & Compliance

For Research Use Only — Not for human or veterinary consumption.
Store sealed in a cool, dry place away from light.
Handle under controlled research-chemical protocols, with secure storage and documentation.
Listed under controlled substances and WADA S1 anabolic agents.
Purchase and handling require qualified researcher compliance with all regulations.